Research
We have an internationally recognised research unit
based at the University of Liverpool
The Liverpool Clinical Trials Centre's portfolio of studies is displayed below.
As part of each study, the LCTC collects information about study participants and research team members – please click here to access the LCTC Privacy Notice which provides more information on how we use Personal Data.
LCTC supports sharing of anonymised data for secondary research. For the studies displayed below which are completed researchers may submit initial queries to lctc@liverpool.ac.uk. Further details on Data Sharing activities by LCTC can be found here on our website.
ACELARATE
A Phase III, open label, multicentre randomised clinical study comparing Acelarin (NUC-1031) with Gemcitabine in patients with metastatic pancreatic carcinoma.
ACIT-1
A Phase I clinical study to determine the optimal dose for the safe immune restoration and immune response of allogeneic cell immunotherapy (ACIT-1) in adult cancer patients.
APPA
A Phase I, Partially Blind, Placebo-Controlled, Ascending Single and Multiple Oral Dose, Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in Healthy Subjects and Osteoarthritis Patients administered APPA-1
APRiCOT
A Pilot Randomised Study to Compare Combination Antibiotic Therapy (Ciprofloxacin, Doxycycline and Hydroxychlororquine) with Standard Therapy (Budesonide) in the Treatment of Active Crohn's Disease
APTITUDE
A phase II trial of Tocilizumab in anti-TNF refractory patients with JIA associated uveitis
ATTAINMENT
A modular, multi-arm, first in human trial to evaluate the safety and tolerability of MDX-124 alone and in combination with anti-cancer treatments, in participants with locally advanced, unresectable or metastatic solid malignancies
BASICS
Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts (BASICS): a multi-centre randomised controlled trial
BESS
the use of surfactant for babies with severe bronchiolitis on PICU
BIOPROP20
Biologically optimised IMRT for Prostate Radiotherapy Hypofractionated radiotherapy with intra-prostatic boosts to tumour nodules in men with intermediate and high risk prostate cancer
BOSS
Investigating Slipped Capital Femoral Epiphysis (SCFE) as a childhood precursor to osteoarthritis of the hip in adulthood: A nationwide service evaluation, and nested-cohort study
CAPER
A Phase Ib clinical trial of Cyclophosphamide And PEmbrolizumab in metastatic Renal cell carcinoma (CAPER Trial)
CASTLE
Randomised factorial design controlled trial comparing carbamazepine, levetiracetam or active monitoring combined with or withou
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Increasing calls for transparency, reproducibility and data sharing within clinical trials have led to a greater emphasis on the early development and publication of well written Statistical Analysis Plans (SAPs).
To address a variation in practice a minimum set of items for SAPs was agreed with funders, regulatory authorities, journals and researchers. A downloadable version of the SAP checklist is available here.